Visiting Cities, Ruins, or Beach Areas  Tufesa Bus runs from the US to Guadalajara, Mexico.

The bus stations in the larger Mexican cities are open 24 / 7. You can arrive in the morning and check your luggage for a small fee. You are then free to travel the city, ruin, or beach with just your daypack. (the Mochila in Mexico)
Tufesa Bus reaches Mazatlan and runs along the Pacific Coast.  Several stops will offer beach towns.  Taxis, collectivos, or local buses can get you to the beach from the Tufesa Terminal.  Mazatlan offers many luxury and mid range hotels.  Also find international  flights, rental cars, and a cruise terminal.

Taxis are usually inexpensive ( $3 to $6 USD)  except in Mexico City. ( 90 peso to go from Mexico Norte Bus Station to Tapo Bus Station,  $9-$10 USD, much more at the airport)
You could also
catch a local bus or collective taxi to the beach or ruin after a little inquiry at the station or some web research.
Colectivos are shared taxis that charge per passenger and offer a better price. Ask where the collectivo passes for your destination and you can save. See addition info on the web at Mexico Transportation: Taxis, Collectivos, Travel.

Some Bus Travel Tips:
  • Keep your daypack with you and your essentials like sweater, computer,
camera, snack , water, etc in the pack in the overhead or under your leg rest. Keep your passport, visa, money, credit cards, ATM cards etc on your person.

  • Don’t share drink or food with strangers. Don;t accept drink or food from strangers.

  • Taxis
Let the starter or concierge arrange for your taxi in Mexico City and in other large cities. The price will be preset and there will be no surprises.
If you are on the street, ask for the taxi stand or go into a hotel and ask the clerk to call a taxi. Let the starter at the bus station arrange for the cab. Always agree on a price before entering.  You avoid Pirate cabs if you let the starter of concierge /desk clerk order the taxi.

  • Share and Save
Invite other travelers to join you and share the price, the taxis charge by the trip not by the number of people.

  • Caution Many bus lines and stations
Tufesa operates from their own stations for the most part but a large city could have more than one bus station; Mexico City Bus Terminals
  • Mexico City has four first class stations.
  • Mazatlan has a Tufesa Station, a Primera Plus, and an ETN,
Write down the name of your station once you arrive and before you catch a taxi to head into the Centro Historico of the city or to the beach or ruin site. These stations might just be a three letter abbreviation (TAM, for instance for Transportation Autobus Moralia, or ADO for the First Class terminal in Oaxaca)  Tapo in Mexico City)
You are apt to forget this after a day of touring or beaching. Write this on your ticket stub and you have the station name and the bus line.
Do the same with your hotel or hostel. Ask at the desk for a card with the name and address. Hand that to a taxi driver when you want to return to the station and you will have no problem.
See
Page Three
Bus Travel Through Mexico includes Cross Border bus service through Nogales aboard Tufesa Bus. Border Crossing at Nogales, Mexico and Tijuana on Tufesa Bus which runs a service from the US that crosses the Mexican Border.  
Bus Travel Through Mexico, Cross Border Tufesa Bus Service
Border Crossing, Nogales, Mexico,
Tufesa Bus runs a service from the Us that crosses the Mexican Border.

This Cross Border Bus can make your bus trip through Mexico easier.

For European, Canadian, and US independent travelers and backpackers, the long- haul first class buses of Mexico offer an alternative to the airliner. The buses have more room and are more comfortable than an airliner. The service in Mexico is plentiful and, other than being a longer trip in terms of time spent traveling, a much more stress-free experience.
Several bus lines make cross border trips  Tufesa runs from Las Vegas, Nevada. Salt Lake City, and several cities in California.

Copper Canyon:  Tufesa Bus stops in Los Mochis, the western train terminal of the Copper Canyon train.
 
  • The Air Conditioning systems are blasting frigid air, bring a sweater or jacket.

  • Earplugs
If you want to sleep, bring earplugs for the movies; you will get either cartoons, Cantinflas specials, or US action flicks.

  • Stop When You Want
The great advantage of bus travel in Mexico over air travel is that you can stop in the small colonial cities or beach towns and resort areas along the way and tour for the day. You can then Taxi back to the bus station, board a night bus and sleep until you reach the next city or beach. If you time it right, you arrive in your next city at dawn (7 am in the tropics) and you start touring the city or you put into a hotel or hostel for an overnight stop.

  • Resume, Bus service is Plentiful with overlap of many bus lines and bus routes.
Mexico's colonial cities offer many hotel options in the historic centers.  Also find flights, rental cars and first class bus service in the larger cities of Mexico.
Bus hub cities like Mexico City, Guadalajara, and Oaxaca  offer many hotel options in the historic centers along with International flights, and rental cars.
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