Beyond Panama south there is
no reliable road. Impassible
dangerous any time the roads
turn to dirt track and only a few
4wd vehicles make the Beyond
Panama south there is
passage through the Darien
passage through the Darien
Gap. Otherwise air or boat is
Gap. Otherwise air or boat is
the only way to reach south
America from Panama.
See article for boat info
With Tica Bus service
through
Central
America
you stay on the
same bus
if you choose
and
cross the borders.  
This can make the trip
safer and simpler.
The
Tica Bus line runs
a total of 38
air-conditioned buses
Cross Border Bus, Central America, Tica Bus Service
Central America Bus
Travel,
The Tica Bus, cross-
border buses with
Luxury Seating at a
Backpackers Price
Bus Central America: Cross borders on the same bus with the
Tica Bus

For independent travelers through Southern Mexico to Central America as
far south as Panama City there is a bus option that takes some of the
anxiety out of crossing the borders and finding the next bus. This system is
called the Tica bus for short and stands for
Tansportes Internacionales
Centroamericanos:

The 2011 ticket price for a trip from Tapachula in Chiapas Mexico to
Panama City Panama in Central America is
$238. USD round trip, paid
in
US Dollars, travelers checks, or the currency of the country only, no
checks or credit cards accepted.

Make reservation
via email and pay when arriving at the terminal.

The
Cross Border trip leaves Mexico and goes through Guatemala to El
Salvador where it stops for the night. The bus then goes to Managua and
stops for the overnight. The bus then makes a day and overnight trip to
Panama.
Schedule for trip South from Tapachula in Chiapas, Mexico.
Leave Tapachula at 7:00 am, arrive at Guatemala at 12:00 noon.

Leave Guatemala at 1:00 p.m,,arrive at El Salvador approximately at
5:00 p.m.

Leave El Salvador at 5:00 a.m,,arrive at Nicaragua approximately
at 5:00 p.m.

Leave Nicaragua at 6:00 a.m,,and 12:00 noon, arrive at Costa Rica
approximately at 4:00 p.m, 5:00 p.m. and 9:00 p.m.

Leave Costa Rica at 10:00 p.m. on the same day and arrive at Panama
at 4 in the afternoon the following day.
Passengers can stop for extended stays in the terminal cities, the ticket is still honored, they must
however make a reservation and reserve a seat to continue. Passengers pay additional for their hostel
or hotel, and food. Other expenses that are the passenger’s responsibility would be the visa and each
country’s customs charge which averages $10

Tica runs a total of 38 air-conditioned, 54-passenger buses that have reclining seats, restrooms, window
curtains, TV and video.
Tica Buses  serve
Central America
between Mexico and
Panama. Buses have
reclining seats,
lavatory, window
curtains, TV and video.
For the cross-border Tica bus, the  trip starts
in Tapachula, Chiapas Mexico with service to
Panama City, Panama in Central America
Cross Border Bus to Central America via the Tica for 2012
has a ticket price from Tapachula, Chiapas Mexico to
Panama City Panama of $254. USD Round trip.
Tica accepts US Dollars, travelers checks, or the currency
of the country, no checks or credit cards

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ADO Bus Sells tickets for Tica Bus to Guatemala In Oaxaca
City first class bus station